ABSTRACT WATCH: Single and multiple food allergies in infants with proctocolitis.

Allergol Immunopathol (Madr). 2018 Jan – Feb;46(1):3-8.

Single and multiple food allergies in infants with proctocolitis.

Koksal BT1, Barıs Z2, Ozcay F2, Yilmaz Ozbek O3.

Abstract

BACKGROUND:
Food protein-induced allergic proctocolitis is a frequent cause of rectal bleeding in infants. Characteristics of infants with multiple food allergies have not been defined.

OBJECTIVE:
This study aimed to identify characteristics of infants with proctocolitis and compare infants with single and multiple food allergies.

METHODS:
A total of 132 infants with proctocolitis were evaluated retrospectively. All of the infants were diagnosed by a paediatric allergist and/or a paediatric gastroenterologist according to guidelines. Clinical features of the infants, as well as results of a complete blood count, skin prick test, specific immunoglobulin E, and stool examinations or colonoscopy were recorded.

RESULTS:
Cow’s milk (97.7%) was the most common allergen, followed by egg (22%). Forty-five (34.1%) infants had allergies to more than one food. Infants with multiple food allergies had a higher eosinophil count (613±631.2 vs. 375±291.9) and a higher frequency of positive specific IgE and/or positive skin prick test results than that of patients with a single food allergy. Most of the patients whose symptoms persisted after two years of age had multiple food allergies.

CONCLUSIONS:
There is no difference in clinical presentations between infants with single and multiple food allergies. However, infants with multiple food allergies have a high blood total eosinophil count and are more likely to have a positive skin prick test and/or positive specific IgE results.

KEYWORDS:
Allergic proctocolitis; Bloody stool; Colonoscopy; Eosinophil count; Multiple food allergies; Skin prick test; Specific immunoglobulin E

 

sumber: pubmed

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